Subscribe to our What's New in Pathology newsletter - next issue on Hematopathology coming out soon. Gonzalez, M. Page views in 5, Cite this page: Gonzalez RS. Squamous cell carcinoma. Accessed September 3rd, WHO officially only recognizes "squamous cell carcinoma" Basaloid variant has also been termed "cloacogenic" or "transitional" "Mucoepidermoid carcinoma" may be used for tumors with prominent mucinous features, although the biology may be different J Gastroenterol ;
Basaloid squamous cell carcinoma of the anus revisited
Basaloid Squamous Cell Carcinoma of the Anus Revisited.
Estimated new cases and deaths from anal, anal canal, and anorectal cancer in the United States in [ 1 ]. The initial evaluation of a patient with anal cancer will include a careful clinical examination of the inguinal region and biopsy of any palpable lymph nodes. Anal cancer is usually curable. Overall, the risk of anal cancer is rising due to increased incidence of human papilloma virus HPV infection.
Journal of Gastroenterology and Hepatology Research
The pathology and results of treatment of 36 cases of basaloid carcinomas of the anal canal are described. This variant of squamous cell carcinoma of the anal region arises from the entodermal-ectodermal junctional zone of the anal canal at or above the dentate line. Basaloid carcinomas have histological characteristics which resemble basal cell carcinoma of the skin, in particular the presence of palisading of the nuclei at the periphery of the clumps of tumour cells, but are potentially metastasizing tumours. They have been subdivided into three grades of malignancy, namely, well-differentiated, moderately differentiated, and anaplastic basaloid carcinoma. It has been shown that cases of well-differentiated and moderately differentiated basaloids have a good prognosis even when lymph node metastasis has already taken place.